Extragalactic Astronomy Russian The spectra of H II regions in the spiral galaxy M101 disc from the Sloan Digital Sky Survey (SDSS) are examined. The spectra of 17 H II regions with the detected auroral oxygen line [O III] λ 436.3 nm are extracted. The intensities of the spectral lines are measured. The oxygen abundances in the HII regions are derived using thase measurements. It is shown that the SDSS spectroscopic data, complemented with the information on the nebular oxygen line [О II] λ 372.7 nm derived from the recently revealed relation between intensities of oxygen lines in spectra of HII regions (ff relation), allow one to determine the oxygen abundances and exactness of these abundances is comparable to those in the classic T_e method. The parameters of the radial oxygen abundance distribution (the central oxygen abundance and the slope of the radial gradient) in the disc are estimated. oxygen abundance, M101, SDSS, spiral galaxy