The parameters of cosmological model with cold dark matter and cosmological constant (ΛCDM) were determined on the basis of three-year cosmic microwave background observations of the space mission WMAP along with some data on large-scale structure of the Universe. The data cover scales from 1 to 10000 Mpc. The best-fit values of NCDM model parameters were obtained by minimization of &hi;² through the Levenberg— Markquardt approach (Ω_Λ= 0.736±0.065, Ω_m= 0.238±0.080, Ω_b= 0.05±0.011, h = 0.68±0.09, σ₈ = 0.73±0.08 and n_s = 0.96±0.015). It is shown that the ΛCDM model with our values of the parameters is in good agreement with the angular power spectrum of cosmic microwave background and with the power spectra of density perturbation estimated from spatial distribution of galaxies, rich galaxies clusters and as well as from the statistics of Ly_α absorption lines in spectra of distant quasars. The accordance of model characteristics of the large-scale structure with observable ones was analized, as well as possible reasons of significant deviations between some of them were considered.